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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| IHC-00375-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
178.00€
|
|||
| IHC-00375 | 100 µl (25 µg) | - |
2 - 8 business days* |
668.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm... more
Product information "Anti-Ki-67 (IHC)"
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes (PubMed:26949251). May play a role in chromatin organization (PubMed:26949251). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed. [The UniProt Consortium]
| Keywords: | Anti-Antigen Ki67 homolog, Anti-Antigen KI-67 homolog, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by monoclonal antibody Ki-67 homolog |
| Supplier: | Bethyl Laboratories |
| Supplier-Nr: | IHC-00375 |
Properties
| Application: | IHC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | mouse |
| Immunogen: | synthetic peptide. The epitope recognized by IHC-00375 maps to a region between residues1650 and 1700 of mouse Ki-67 using the numbering given in entry CAA58026.1 (GeneID 17345). |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K17582 | Matching products |
| UniProt ID : | E9PVX6 | Matching products |
| Gene ID : | GeneID 17345 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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