Anti-KDM7A / JHDM1D

Anti-KDM7A / JHDM1D
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG40753.100 100 µl - -

6 - 14 business days*

658.00€
 
Protein function: Histone demethylase required for brain development. Specifically demethylates... more
Product information "Anti-KDM7A / JHDM1D"
Protein function: Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate. [The UniProt Consortium]
Keywords: Anti-Kdm7a, Anti-Jhdm1d, EC=1.14.11.-, Anti-Lysine-specific demethylase 7, Anti-Lysine-specific demethylase 7A, Anti-JmjC domain-containing histone demethylation protein 1D
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG40753

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant fusion protein corresponding to aa. 417-735 of Mouse KDM7A (NP_001028602.2)
MW: 106 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-KDM7A / JHDM1D"
Write a review
or to review a product.
Viewed