Anti-KDM6B / JMJD3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59524.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3,... more

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Product information "Anti-KDM6B / JMJD3"

Protein function: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member- dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex (PubMed:21095589). [The UniProt Consortium]

Keywords:	Anti-Kdm6b, Anti-Jmjd3, EC=1.14.11.-, Anti-Lysine-specific demethylase 6B, Anti-JmjC domain-containing protein 3, Anti-Jumonji domain-containing protein 3
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59524

Properties

Application:	ICC, IF, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Recombinant fusion protein corresponding to aa. 90-190 of Mouse KDM6B / JMJD3 (NP_001017426.1)
MW:	176 kD
Format:	Affinity Purified