Anti-KDM6B / JMJD3

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG54857.100	100 µl		-	-	6 - 14 business days*		30 %	624.00€ 436.80€

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Protein function: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3,... more

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Product information "Anti-KDM6B / JMJD3"

Protein function: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Demethylates trimethylated and dimethylated H3 'Lys-27' (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex. [The UniProt Consortium]

Keywords:	Anti-KDM6B, Anti-JMJD3, Anti-Lysine demethylase 6B, Anti-Lysine-specific demethylase 6B, Anti-JmjC domain-containing protein 3, Anti-Jumonji domain-containing protein 3
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG54857

Properties

Application:	ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	KLH-conjugated synthetic peptide corresponding to aa. 1-30 (N-terminus) of Human JMJD3
Format:	Purified