Anti-KDM6B / JMJD3

Anti-KDM6B / JMJD3
Anti-KDM6B / JMJD3
Anti-KDM6B / JMJD3
     
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Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
ARG54857.100 100 µl - -

6 - 14 business days*

30 %
624.00€
436.80€
 
Protein function: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3,... more
Product information "Anti-KDM6B / JMJD3"
Protein function: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Demethylates trimethylated and dimethylated H3 'Lys-27' (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex. [The UniProt Consortium]
Keywords: Anti-KDM6B, Anti-JMJD3, Anti-Lysine demethylase 6B, Anti-Lysine-specific demethylase 6B, Anti-JmjC domain-containing protein 3, Anti-Jumonji domain-containing protein 3
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG54857

Properties

Application: ICC, IF, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse)
Immunogen: KLH-conjugated synthetic peptide corresponding to aa. 1-30 (N-terminus) of Human JMJD3
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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