Anti-KDM5C / Jarid1C / SMCX, clone 2E4-E1-G8

Anti-KDM5C / Jarid1C / SMCX, clone 2E4-E1-G8

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG53982.100	100 µl		-	-	6 - 14 business days*		30 %	624.00€ 436.80€

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Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3,... more

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Product information "Anti-KDM5C / Jarid1C / SMCX, clone 2E4-E1-G8"

Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2. [The UniProt Consortium]

Keywords:	Anti-KDM5C, Anti-DXS1272E, EC=1.14.11.-, Anti-Protein SmcX, Anti-Protein Xe169, Anti-Histone demethylase JARID1C, Anti-Lysine-specific demethylase 5C, Anti-Jumonji/ARID domain-containing protein 1C
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG53982

Properties

Application:	WB, ICC, IF
Antibody Type:	Monoclonal
Clone:	2E4-E1-G8
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Purified recombinant human KDM5C / Jarid1C / SMCX protein fragments expressed in E.coli
Format:	Affinity Purified