Anti-KDM5C

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA038244.25 25 µl -

7 - 10 business days*

335.00€
ATA-HPA038244.100 100 µl -

7 - 10 business days*

446.00€
 
Protein function: Histone demethylase that specifically demethylates 'Lys-4' of histone H3,... more
Product information "Anti-KDM5C"
Protein function: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code (PubMed:28262558). Does not demethylate histone H3 'Lys-9', H3 'Lys- 27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 77% and to rat: 78%
Keywords: Anti-Protein SmcX, Anti-Protein Xe169, Anti-Histone demethylase JARID1C, Anti-Lysine-specific demethylase 5C, Anti-Jumonji/ARID domain-containing protein 1C, Anti-[histone H3]-trimethyl-L-lysine(4) demethylase 5C
Supplier: Atlas Antibodies
Supplier-Nr: HPA038244

Properties

Application: ICC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EELEPKRVRS SGPEAEEVQE EEELEEETGG EGPPAPIPTT GSPSTQENQN GLEPAEGTTS GPSAPFSTLT PRLH (ATA-APrEST89368)

Database Information

KEGG ID : K11446 | Matching products
UniProt ID : P41229 | Matching products
Gene ID : GeneID 8242 | Matching products
Protein Atlas Nr. : ENSG00000126012

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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