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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Several different potassium channels are known to be involved with electrical signaling in the... more
Product information "Anti-KCNJ4"
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. Protein function: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. [The UniProt Consortium]
Keywords: | Anti-HIR, Anti-IRK3, Anti-HRK1, Anti-IRK-3, Anti-KCNJ4, Anti-HIRK2, Anti-Hippocampal inward rectifier, Anti-Inward rectifier K(+) channel Kir2.3, Anti-Inward rectifier potassium channel 4, Anti-Potassium channel, inwardly rectifying subfamily J member 4, |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-64894 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | A synthetic peptide of human KCNJ4 |
Database Information
KEGG ID : | K04998 | Matching products |
UniProt ID : | P48050 | Matching products |
Gene ID : | GeneID 3761 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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