Anti-KCNH2 / ERG-1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ7086 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. KCNH2, also known as ERG-1, H-ERG or... more
Product information "Anti-KCNH2 / ERG-1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. KCNH2, also known as ERG-1, H-ERG or KV11.1, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel. It is mapped to 7q36.1. KCNH2 forms the major portion of one of the ion channel proteins (the 'rapid' delayed rectifier current (IKr)) that conducts potassium (K+) ions out of the muscle cells of the heart (cardiac myocytes), and this current is critical in correctly timing the return to the resting state (repolarization) of the cell membrane during the cardiac action potential. What?s more, KCNH2 channels show gating properties consistent with many of the outwardly rectifying potassium channels, but they also have an inactivation mechanism that attenuates efflux during depolarization. Protein function: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (PubMed:18559421, PubMed:26363003, PubMed:27916661). [The UniProt Consortium]
Keywords: Anti-ERG, Anti-KCNH2, Anti-H-ERG, Anti-hERG1, Anti-ERG-1, Anti-hERG-1, Anti-Eag homolog, Anti-Eag-related protein 1, Anti-Ether-a-go-go-related protein 1, Anti-Ether-a-go-go-related gene potassium channel 1, KCNH2 Antibody / ERG-1
Supplier: NSJ Bioreagents
Supplier-Nr: RQ7086

Properties

Application: WB, FC, Direct ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant human protein (amino acids A121-V1074)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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