Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
![Anti-JMJD2A](https://www.biomol.com/media/image/f9/b0/4a/Cay10382-1_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10382-1 | 500 µl | - |
6 - 10 business days* |
422.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Jumonji Domain Containing 2A (JMJD2A) is a lysine-specific demethylase that catalyzes the... more
Product information "Anti-JMJD2A"
Jumonji Domain Containing 2A (JMJD2A) is a lysine-specific demethylase that catalyzes the demethylation of histone H3 at lysine residues 9 and 36 and histone H1.4 at lysine residue 26. It is composed of the JmjN N-terminal domain, JmjC catalytic domain, two plant homeodomains (PHDs), and two tudor domains that recognize the methylated histones. JMJD2A is ubiquitously expressed and localized to the nucleus. It is involved in the regulation of gene expression in a context-dependent manner, having roles in both transcriptional silencing and activation of androgen and estrogen receptors (ERs). Knockdown of JMJD2A inhibits the proliferation of ER-positive and -negative breast cancer cells and induces apoptosis and cell cycle arrest in colon cancer cells. It is overexpressed in various cancers, including prostate, lung, and colorectal, as well as glioblastomas and endometrial carcinomas, and is associated with higher tumor grade and decreased disease-free survival in breast cancer. Cayman's JMJD2A Polyclonal Antibody can be used for Western blot (WB). The antibody recognizes JMJD2A at 135 kDa from human samples.Synonyms: JHDM3A, Jumonji Domain Containing 2A, KDM4A, Lysine (K)-specific Demethylase 4A. Immunogen: Human recombinant JMJD2A amino acids 1-350. Amino Acids: 1-350. MW: 135 kDa. Formulation: (Request formulation change), 500 µl of protein A purified polyclonal polyclonal antibody. Storage Buffer: TBS, pH 7.4, with 50% glycerol, 0.1% BSA, and 0.02% sodium azide. Host: Rabbit. Applications: WB. Cross Reactivity: (+) JMJD2C, (+) JMJD2B. UniProt Accession #: O75164. Origin: Animal/Rabbit.
Keywords: | Anti-KDM4A, Anti-JHDM3A, Anti-Lysine-specific demethylase 4A, Anti-Lysine-specific demethylase 4A, Anti-Jumonji domain-containing protein 2A, Anti-Jumonji domain-containing protein 2A, Anti-JmjC domain-containing histone demethylation protein 3A, Anti-Jmj |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10382 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Human recombinant JMJD2A amino acids 1-350 |
Format: | Purified |
Database Information
KEGG ID : | K06709 | Matching products |
UniProt ID : | O75164 | Matching products |
Gene ID | GeneID 9682 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed