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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-475A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
178.00€
|
|||
A301-475A | 100 µl | - |
2 - 8 business days* |
630.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Histone demethylase that specifically demethylates 'Lys- 36' of histone H3,... more
Product information "Anti-JHDM1A"
Protein function: Histone demethylase that specifically demethylates 'Lys- 36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys- 36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. [The UniProt Consortium]
Keywords: | Anti-KDM2A, Anti-CXXC8, EC=1.14.11.27, Anti-F-box protein FBL7, Anti-F-box protein Lilina, Anti-F-box/LRR-repeat protein 11, Anti-Lysine-specific demethylase 2A, Anti-CXXC-type zinc finger protein 8, Anti-[Histone-H3]-lysine-36 demethylase 1A |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-475A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, gorilla, chimpanzee, white-tufted-ear marmoset, naked mole rat, small-eared galago, little brown bat, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A301-475A-T maps to a region between residue 825 and 875 of human JmjC domain-containing histone demethylation protein 1A using the numbering given in entry NP_036440.1 (GeneID 22992). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K10276 | Matching products |
UniProt ID : | Q9Y2K7 | Matching products |
Gene ID : | GeneID 22992 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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