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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
J7876-21A.100 | 100 µg | - | - |
3 - 19 business days* |
962.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Jumonji [Japanese for "cruciform/cross" also JARID2 (Jumonji/ARID domain-containing protein 2)... more
Product information "Anti-JARID2 (Protein Jumonji, Jumonji/ARID Domain-containing Protein 2, JMJ)"
Jumonji [Japanese for "cruciform/cross" also JARID2 (Jumonji/ARID domain-containing protein 2) and JMJ] is a 140-155kD member of the JMJ family of proteins. It is a nuclear complex coordinator that interacts with the G9a and GLP methyltransferases to repress gene transcription. Jumonji is expressed in mammalian embryonic neurons, megakaryocytes, hepatocytes and cardiomyocytes. Human Jumonji is 1246aa in length. It contains an NLS (aa1-131), a transcriptional repressor domain (aa132-222), a DNA binding region (aa558-709) and a nonfunctional histone demethylase domain (aa916-1042). There are potential splice variants. One shows an alternative start site at Met173, another shows a deletion of aa304-1151, and a third contains a 22aa substitution foraa1-60, coupled to a 50aa substitution for aa949-1246. Over aa1-159, human Jumonji shares 96% aa identity with mouse Jumonji. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 0.5-1ug/ml, Western Blot: 0.1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-Jumonji/ARID domain-containing protein 2 |
Supplier: | United States Biological |
Supplier-Nr: | J7876-21A |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Sheep |
Species reactivity: | human, mouse |
Immunogen: | Purified, E. coli-derived, recombinant human Jumonji (rhJumonji, aa 1 - 159, Accession # Q92833). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K11478 | Matching products |
UniProt ID : | Q92833 | Matching products |
Gene ID : | GeneID 3720 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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