Anti-JARID2

Anti-JARID2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-25295 100 µl - -

3 - 15 business days*

706.00€
 
JARID2 (UniProtKB/Swiss Prot entry Q92833) is a regulator of histone methyltransferase complexes... more
Product information "Anti-JARID2"
JARID2 (UniProtKB/Swiss Prot entry Q92833) is a regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. JARID2 acts by recruiting histone methyltransferase complexes (PRC2) to their target genes and modulating the histone methyltransferase activity. It does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of H3K27me3 by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin D1 (CCND1) by activating H3K9 methylation by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases.
Keywords: JMJ,
Supplier: BPS Bioscience
Supplier-Nr: 25295

Properties

Application: ELISA
Antibody Type: Polyclonal
Conjugate: No
Species reactivity: human
Immunogen: human JARID2 (jumonji, AT rich interactive domain 2) using two KLH conjugated synthetic peptides containing a sequence from the N terminal and the central region of the protein, respectively.
Format: Serum

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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Anti-JARID2 Anti-JARID2
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