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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-25295 | 100 µl | - | - |
3 - 15 business days* |
706.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
JARID2 (UniProtKB/Swiss Prot entry Q92833) is a regulator of histone methyltransferase complexes... more
Product information "Anti-JARID2"
JARID2 (UniProtKB/Swiss Prot entry Q92833) is a regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. JARID2 acts by recruiting histone methyltransferase complexes (PRC2) to their target genes and modulating the histone methyltransferase activity. It does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of H3K27me3 by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin D1 (CCND1) by activating H3K9 methylation by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases.
Keywords: | JMJ, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 25295 |
Properties
Application: | ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Species reactivity: | human |
Immunogen: | human JARID2 (jumonji, AT rich interactive domain 2) using two KLH conjugated synthetic peptides containing a sequence from the N terminal and the central region of the protein, respectively. |
Format: | Serum |
Database Information
KEGG ID : | K11478 | Matching products |
UniProt ID : | Q92833 | Matching products |
Gene ID : | GeneID 3720 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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