Anti-JARID1C

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-034A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A301-034A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3,... more

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Product information "Anti-JARID1C"

Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2. [The UniProt Consortium]

Keywords:	Anti-KDM5C, Anti-DXS1272E, EC=1.14.11.-, Anti-Protein SmcX, Anti-Protein Xe169, Anti-Histone demethylase JARID1C, Anti-Lysine-specific demethylase 5C, Anti-Jumonji/ARID domain-containing protein 1C
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-034A

Properties

Application:	WB, IP, ChIP-Seq
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: dog, pig)
Immunogen:	synthetic peptide. The epitope recognized by A301-034A-T maps to a region between residue 275 and 325 of human Jumonji, AT rich interactive domain 1C using the numbering given in entry NP_004178.2 (GeneID 8242).
Format:	Antigen Affinity Purified