Anti-Jarid1c

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
100-401-W42	100 µl		-	-	6 - 10 business days*		641.00€

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Anti-Jarid1c Antibody is monospecific antiserum processed by delipidation and defibrination... more

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Product information "Anti-Jarid1c"

Anti-Jarid1c Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with Jarid1c from other species not tested. Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2. [The UniProt Consortium]

Keywords:	Anti-KDM5C, Anti-DXS1272E, EC=1.14.11.-, Anti-Protein SmcX, Anti-Protein Xe169, Anti-Histone demethylase JARID1C, Anti-Lysine-specific demethylase 5C, Anti-Jumonji/ARID domain-containing protein 1C
Supplier:	Rockland Immunochemicals
Supplier-Nr:	100-401-W42

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse, human
Immunogen:	Three different synthetic peptides containing sequences from the inner part of the mouse Jarid1c protein.
Format:	Antiserum