Anti-Jarid1b

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
100-401-V92	100 µl		-	-	6 - 10 business days*		641.00€

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Anti-Jarid1b Antibody is monospecific antiserum processed by delipidation and defibrination... more

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Product information "Anti-Jarid1b"

Anti-Jarid1b Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with Jarid1b from other species not tested. Protein function: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2. [The UniProt Consortium]

Keywords:	Anti-CT31, Anti-KDM5B, Anti-PLU-1, Anti-RBP2-H1, Anti-JARID1B, EC=1.14.11.-, Anti-Cancer/testis antigen 31, Anti-Histone demethylase JARID1B, Anti-Lysine-specific demethylase 5B, Anti-Jumonji/ARID domain-containing protein 1B, Anti-Retinoblastoma-binding
Supplier:	Rockland Immunochemicals
Supplier-Nr:	100-401-V92

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse
Immunogen:	Synthetic peptide containing an amino acid sequence from the internal part of mouse Jarid1b.
Format:	Antiserum