Anti-JAK1, clone 7G6

Item number	Size	Manual	Delivery time	Price
E-AB-22202.20	20 µl	-	7 - 16 business days*	72.00€
E-AB-22202.60	60 µl	-	7 - 16 business days*	142.00€
E-AB-22202.120	120 µl	-	7 - 16 business days*	238.00€
E-AB-22202.200	200 µl	-	7 - 16 business days*	395.00€

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Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway.... more

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Product information "Anti-JAK1, clone 7G6"

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. Protein function: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:8232552, PubMed:7615558, PubMed:28111307, PubMed:32750333, PubMed:16239216). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529) as well as interleukin (IL)-10 receptor (PubMed:12133952). Kinase partner for the type I interferon receptor IFNAR2 (PubMed:8232552, PubMed:7615558, PubMed:28111307, PubMed:32750333, PubMed:16239216). In response to interferon-binding to IFNAR1-IFNAR2 heterodimer, phosphorylates and activates its binding partner IFNAR2, creating docking sites for STAT proteins (PubMed:7759950). Directly phosphorylates STAT proteins but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors (PubMed:8232552, PubMed:16239216, PubMed:32750333). [The UniProt Consortium]

Keywords:	Anti-JAK1, Anti-JAK-1, Anti-JAK1A, Anti-Janus kinase 1, Anti-Tyrosine-protein kinase JAK1, JAK1 Monoclonal Antibody
Supplier:	Elabscience
Supplier-Nr:	E-AB-22202

Properties

Application:	IHC (paraffin)
Antibody Type:	Monoclonal
Clone:	7G6
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic Peptide of JAK1
Format:	Purified