Anti-ISL1

Anti-ISL1
Cancer Research
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-AMAb91729.25 25 µl -

7 - 10 business days*

300.00€
ATA-AMAb91729.100 100 µl -

7 - 10 business days*

421.00€
 
Protein function: DNA-binding transcriptional activator. Recognizes and binds to the consensus... more
Product information "Anti-ISL1"
Protein function: DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences. Essential for heart development. Marker of one progenitor cell population that give rise to the outflow tract, right ventricle, a subset of left ventricular cells, and a large number of atrial cells as well, its function is required for these progenitors to contribute to the heart. Controls the expression of FGF and BMP growth factors in this cell population and is required for proliferation and survival of cells within pharyngeal foregut endoderm and adjacent splanchnic mesoderm as well as for migration of cardiac progenitors into the heart. [The UniProt Consortium] Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Keywords: Anti-ISL1, Anti-Islet-1, Anti-Insulin gene enhancer protein ISL-1
Supplier: Atlas Antibodies
Supplier-Nr: AMAb91729

Properties

Application: ICC
Antibody Type: Monoclonal
Conjugate: No
Host: Mouse
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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