Anti-IRE1p

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-BZ6	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-IRE1p Antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-IRE1p"

Anti-IRE1p Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with IRE1p from other sources has not been determined. Protein function: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. [The UniProt Consortium]

Keywords:	Anti-IRE1a, Anti-hIRE1p, Anti-Ire1-alpha, EC=2.7.11.1, EC=3.1.26.-, Anti-Endoribonuclease, Anti-Inositol-requiring protein 1, Anti-Serine/threonine-protein kinase, Anti-Endoplasmic reticulum-to-nucleus signaling 1, Anti-Serine/threonine-protein kinase/end
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-BZ6

Properties

Application:	ELISA, IHC, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	16 amino acid synthetic peptide from near the C-terminus of human IRE1p.
Format:	Purified