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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
I8443-17B.100 | 100 µg | - | - |
3 - 19 business days* |
1,137.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Interleukin22 (IL22), also known as IL10related T cellderived inducible factor (ILTIF) was... more
Product information "Anti-Interleukin 22 (IL-22, IL-10 Related T cell-derived Inducible Factor, IL-TIF) (Biotin)"
Interleukin22 (IL22), also known as IL10related T cellderived inducible factor (ILTIF) was initially identified as a gene induced by IL9 in mouse T cells and mast cells. Human IL22 cDNA encodes a 179 aa residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with mouse IL22 and human IL10, respectively. The human IL22 gene is localized to chromosome 12q15. Although it exists as a single copy gene in human and in many mouse strains, the mouse IL22 gene is duplicated in some mouse strains including C57B1/6, FVB and 129. The two mouse genes designated ILTIF-alpha and ILTIF-beta, share greater than 98% sequence homology in their coding region. IL22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL22 is produced by normal T cells upon antiCD3 stimulation in humans. Mouse IL22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL22 may be involved in inflammatory responses. The functional IL22 receptor complex consists of two receptor subunits, IL22R (previously an orphan receptor named CRF29) and IL10 R-beta (previously known as CRF24), belonging to the class II cytokine receptor family. Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: ELISA: 0.5-2ug/ml when used as detection antibody and paired with I8443-17A (used at 2-8ug/ml) as capture antibody., Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: | United States Biological |
Supplier-Nr: | I8443-17B |
Properties
Application: | ELISA |
Antibody Type: | Monoclonal |
Clone: | 142928 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Database Information
KEGG ID : | K05445 | Matching products |
UniProt ID : | Q9GZX6 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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