Anti-IL-6 antibody(DMC419), IgG1 Chimeric mAb

Item number	Size	Manual	SDS	Delivery time	Price
DIM-DMC100419.10	10 µg	-	-	7 - 16 business days*	139.00€
DIM-DMC100419.100	100 µg	-	-	7 - 16 business days*	624.00€
DIM-DMC100419.500	500 µg	-	-	7 - 16 business days*	1,876.00€

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Protein function: Cytokine with a wide variety of biological functions in immunity, tissue... more

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Product information "Anti-IL-6 antibody(DMC419), IgG1 Chimeric mAb"

Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans- signaling'. Alternatively, 'cluster signaling' occurs when membrane- bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). [The UniProt Consortium]

Keywords:	Anti-IL6, Anti-Interleukin-6, Anti-BSF2, Anti-HSF, Anti-IFNB2, Anti-IL-6 antibody(DMC419), IgG1 Chimeric mAb
Supplier:	DIMA
Supplier-Nr:	DMC100419

Properties

Antibody Type:	Monoclonal
Clone:	DMC419
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Format:	Lyophilized

Database Information

CAS :	12\| Matching products
KEGG ID :	K05405 \| Matching products
UniProt ID :	P05231 \| Matching products
Gene ID	GeneID 3569 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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