Anti-IKZF4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA046270.25	25 µl		-		7 - 10 business days*		320.00€
ATA-HPA046270.100	100 µl		-		7 - 10 business days*		450.00€

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Protein function: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros- binding sequence.... more

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Product information "Anti-IKZF4"

Protein function: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros- binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3- mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 90% and to rat: 91%

Keywords:	Anti-IKZF4, Anti-KIAA1782, Anti-Zinc finger protein Eos, Anti-Ikaros family zinc finger protein 4
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA046270

Properties

Application:	ICC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VNSGGYEKDV ELVAHHSLEP GFGSSLAFVG AEHLRPLRLP PTNCISELTP VISSVYTQMQ PLPGRLELPG SREAGEGPED LADGGPLLYR PRGPLTDPGA (ATA-APrEST89523)