Save 30% on all primary antibodies by Arigo Biolaboratories!
*1Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
ARG66320.100 | 100 µl | - | - |
6 - 14 business days* |
30 %
|
624.00€
436.80€ |
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Protein function: Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'- linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B- mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response, this function requires 'Lys-27'-linked polyubiquitination. [The UniProt Consortium]
Keywords: | Anti-NEMO, Anti-IKKG, Anti-FIP3, Anti-IKBKG, Anti-FIP-3, Anti-IKKAP1, Anti-IKK-gamma, Anti-IkB kinase subunit gamma, Anti-NF-kappa-B essential modifier, Anti-NF-kappa-B essential modulator, Anti-I-kappa-B kinase subunit gamma |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG66320 |
Properties
Application: | FC, IHC (paraffin), IP, WB |
Antibody Type: | Monoclonal |
Clone: | SQab1868 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Synthetic peptide around the N-terminus of IKK gamma |
MW: | 48 kD |
Format: | Purified |
Database Information
KEGG ID : | K07210 | Matching products |
UniProt ID : | Q9Y6K9 | Matching products |
Gene ID : | GeneID 8517 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Our products are for laboratory research use only: Not for administration to humans!