Anti-IFT57

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA035514.100	100 µl		-		7 - 10 business days*		477.00€

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Protein function: Required for the formation of cilia. Plays an indirect role in sonic hedgehog... more

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Product information "Anti-IFT57"

Protein function: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'- AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 93% and to rat: 94%

Keywords:	Anti-IFT57, Anti-DERP8, Anti-MHS4R2, Anti-HIP1-interacting protein, Anti-Dermal papilla-derived protein 8, Anti-Intraflagellar transport protein 57 homolog, Anti-Estrogen-related receptor beta-like protein 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA035514

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RSFGRTADFP PSKLKSGYGE HVCYVLDCFA EEALKYIGFT WKRPIYPVEE LEEESVAEDD AELTLNKVDE EFVEEETDNE ENFIDLN (ATA-APrEST79325)