Anti-IARS

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-747A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A304-747A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

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Protein function: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate... more

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Product information "Anti-IARS"

Protein function: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]

Keywords:	Anti-IRS, Anti-IARS, Anti-IleRS, EC=6.1.1.5, Anti-Isoleucyl-tRNA synthetase, Anti-Isoleucine--tRNA ligase, cytoplasmic
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-747A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: gorilla, chimpanzee)
Immunogen:	synthetic peptide. The epitope recognized by A304-747A-T maps to a region between residue 1 to 50 of human Isoleucyl-tRNA Synthetase using the numbering given in entry NP_002152.2 (GeneID 3376).
Format:	Antigen Affinity Purified