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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-43-1104-100 | 100 µg | - |
3 - 11 business days* |
708.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The H74 monoclonal antibody binds to human B7-H4, a newly discovered member of the B7 family... more
Product information "Anti-Human B7-H4 NALE(TM) Purified (Clone: H74)"
The H74 monoclonal antibody binds to human B7-H4, a newly discovered member of the B7 family involved with the negative regulation of T cell immunity. B7-H4 is a type I membrane glycoprotein also known as B7S1, B7X, and VCTN1. Its role in tumor progression may be to protect precancerous cells from the surveillance of the immune system. Further studies are being conducted to determine the exact B7-H4 ligand. It is reported that the H74 antibody binds to human B7-H4 transfected cells and not peripheral blood cells. Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. [The UniProt Consortium]
Keywords: | Anti-B7-H4, Anti-B7h.5, Anti-Protein B7S1, Anti-B7 homolog 4, Anti-T-cell costimulatory molecule B7x, Anti-Immune costimulatory protein B7-H4, Anti-V-set domain-containing T-cell activation inhibitor 1, Monoclonal Antibody to Human B7-H4 NALE(TM) Purified |
Supplier: | Abeomics |
Supplier-Nr: | 43-1104 |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | H74 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06747 | Matching products |
UniProt ID : | Q7Z7D3 | Matching products |
Gene ID | GeneID 79679 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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