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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-10-7599-NALE-100 | 100 µg | - | - |
3 - 11 business days* |
418.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belongs to the B7... more
Product information "Anti-hPD-L1 (Clone: ABM5F25) (NALE(TM) No Azide Low Endotoxin)"
PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belongs to the B7 superfamily that inhibits immune responses through its receptor, PD-1 and PD-L1 play a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS), may co-stimulate T cells and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion, facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection, inflammation and in numerous autoimmune diseases. Protein function: Involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. [The UniProt Consortium]
Keywords: | Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death ligand 1, Anti-Programmed cell death 1 ligand 1, NALE Monoclonal antibody to hPD-L1 (Clone: ABM5F25) (No Azide Low Endotoxin) |
Supplier: | Abeomics |
Supplier-Nr: | 10-7599-NALE |
Properties
Application: | FC, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | ABM5F25 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A partial length recombinant protein of PD-L1 (amino acid 13-224) was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K06745 | Matching products |
UniProt ID : | Q9NZQ7 | Matching products |
Gene ID | GeneID 29126 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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