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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay21827-100 | 100 µg | - |
6 - 10 business days* |
456.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
HLA-DR is a MHC Class II cell surface receptor heterodimer composed of a 33-35 kDa alpha chain, a... more
Product information "Anti-HLA-DR (Clone L243)"
HLA-DR is a MHC Class II cell surface receptor heterodimer composed of a 33-35 kDa alpha chain, a ~30 kDa beta chain, and a 10-30 amino acid ligand. When the heterodimer is fully combined on the cell surface of an antigen-presenting cell, such as macrophages, B cells, and dendritic cells, they present that ligand primarily to CD-4+ T cells. This presentation coupled with the T cell response can stimulate or suppress an antibody response to that ligand. HLR-DRs have been linked to a number of autoimmune disorders such as rheumatoid arthritis, lupus, and psoriasis as well as diabetes, hepatitis, and sclerosis among a number of others. Cayman's HLA-DR Monoclonal Antibody (Clone L243) detects HLA-DR with or without attached ligand. The predicated size of the HLA-DRalpha or HLA-DRbeta subunits is ~29-30 kDa.Synonyms: HLA Class II Histocompatibility Antigen DR, MHC Class II Antigen DR. Immunogen: Human lymphoblastoid cell line (RPMI 8866). Clone Designation: L243. Formulation: (Request formulation change), 100 µg of protein G-purified IgG. Storage Buffer: PBS, pH 7.2, containing 50% glycerol, with 0.1% BSA, and 0.02% sodium azide. Host: Mouse. Isotype: IgG2a. Applications: FC, ICC, IF, IHC, IP, and WB.
Keywords: | HLA Class II Histocompatibility Antigen DR, MHC Class II Antigen DR |
Supplier: | Cayman Chemical |
Supplier-Nr: | 21827 |
Properties
Application: | FC, ICC, IF, IHC, IP, WB |
Antibody Type: | Monoclonal |
Clone: | L243 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, primates, dog |
Immunogen: | Human lymphoblastoid cell line (RPMI 8866) |
Format: | Purified |
Database Information
KEGG ID : | K06752 | Matching products |
UniProt ID : | P01903 | Matching products |
Gene ID : | GeneID 3122 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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