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![Anti-Histone H2B pan](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-X47 | 50 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-Histone H2B pan Antibody was purified by affinity purification. Cross reactivity with other... more
Product information "Anti-Histone H2B pan"
Anti-Histone H2B pan Antibody was purified by affinity purification. Cross reactivity with other species was not tested. Protein function: Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells. Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones. Also expressed maternally and is present in the female pronucleus, suggesting a similar role in protamine replacement by nucleosomes at fertilization. Also found in fat cells, its function and the presence of post-translational modifications specific to such cells are still unclear. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]
Keywords: | Anti-TSH2B, Anti-TSH2B.1, Anti-HIST1H2BA, Anti-Histone H2B, testis, Anti-Histone H2B type 1-A, Anti-Testis-specific histone H2B |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-X47 |
Properties
Application: | ELISA, ChIP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic peptide containing a sequence from the C-terminus of histone H4. |
Format: | Purified |
Database Information
KEGG ID : | K11252 | Matching products |
UniProt ID : | Q96A08 | Matching products |
Gene ID | GeneID 255626 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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