Anti-HIF2-alpha Recombinant Monoclonal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A700-003-T	20 µl (2 blots)		-		2 - 8 business days*		185.00€
A700-003	100 µl (10 blots)		-		2 - 8 business days*		445.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Transcription factor involved in the induction of oxygen regulated genes. Binds... more

Close menu

Product information "Anti-HIF2-alpha Recombinant Monoclonal"

Protein function: Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD. [The UniProt Consortium]

Keywords:	Anti-HLF, Anti-EPAS1, Anti-EPAS-1, Anti-BHLHE73, Anti-bHLHe73, Anti-HIF2-alpha, Anti-HIF-2-alpha, Anti-HIF-1-alpha-like factor, Anti-Member of PAS protein 2, Anti-PAS domain-containing protein 2, Anti-Hypoxia-inducible factor 2-alpha
Supplier:	Bethyl Laboratories
Supplier-Nr:	A700-003

Properties

Application:	WB, IP, IHC, ICC, ICC-IF, ChIP-Seq
Antibody Type:	Monoclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	synthetic peptide.
Format:	Antigen Affinity Purified