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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F40371-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F40371-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. Hepatocyte Growth Factor regulates cell growth, cell... more
Product information "Anti-HGF, clone 489CT6.12.6"
In 1X PBS, pH 7.4, with 0.09% sodium azide. Hepatocyte Growth Factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 64-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq]. Protein function: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. [The UniProt Consortium]
Keywords: | Anti-HGF, Anti-HPTA, HGF Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F40371 |
Properties
Application: | WB, ELISA |
Antibody Type: | Monoclonal |
Clone: | 489CT6.12.6 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A portion of amino acids 521-554 from the human protein was used as the immunogen for this HGF antibody. |
Format: | Purified |
Database Information
KEGG ID : | K05460 | Matching products |
UniProt ID : | P14210 | Matching products |
Gene ID : | GeneID 3082 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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