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![Anti-HDAC3](https://www.biomol.com/media/image/a2/5d/69/Cay13493-1_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay13493-1 | 1 each | - |
6 - 10 business days* |
413.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Histone deacetylase 3 (HDAC3) is a zinc-dependent metalloenzyme and class I HDAC. It is... more
Product information "Anti-HDAC3"
Histone deacetylase 3 (HDAC3) is a zinc-dependent metalloenzyme and class I HDAC. It is ubiquitously expressed and localizes primarily to the nucleus but also to the cytoplasm and plasma membrane. HDAC3 forms a complex with nuclear receptor co-repressor (NCOR) and silencing mediator of retinoic thyroid receptors (SMRT) to deacetylate histones and induce transcriptional repression and can be recruited to sites bound by activating transcription factor 2 (ATF2) without NCOR to induce inflammatory gene expression, indicating a role in transcriptional activation. HDAC3 activity is correlated with various diseases, including cancer, metabolic disorders, autoimmune disorders, neurodegenerative and CNS disorders, and cardiovascular disease. Cayman's HDAC3 Polyclonal Antibody can be used for chromatin immunoprecipitation (CHiP), immunoprecipitation (IP), and Western blot (WB) applications.Synonyms: Histone Deacetylase 3, KDAC, RPD3. Immunogen: Synthetic peptide corresponding to human HDAC3 (2-17). Formulation: (Request formulation change), 100 µg of protein G-affinity purified polyclonal antibody. Storage Buffer: PBS, with 0.02% sodium azide. Host: Rabbit. Isotype: IgG. Applications: CHiP, IP, WB. Cross Reactivity: (+) HDAC3.
Keywords: | Histone Deacetylase 3 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 13493 |
Properties
Application: | WB, IP, ChIP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | synthetic peptide corresponding to amino acids 2-17 of human HDAC3 |
Format: | Purified |
Database Information
KEGG ID : | K11404 | Matching products |
UniProt ID : | O15379 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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