Anti-GTF3C3

The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene.GTF3C3 (General Transcription Factor IIIC Subunit 3) is a Protein Coding gene. Diseases associated with GTF3C3 include Tooth Agenesis. Among its related pathways are Gene Expression and RNA Polymerase III Transcription Initiation. Protein function: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. [The UniProt Consortium]