Anti-GSDMD, clone 6D11

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG43428.50	50 µg		-	-	6 - 14 business days*		30 %	520.00€ 364.00€

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Protein function: [Gasdermin-D]: Precursor of a pore-forming protein that plays a key role in... more

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Product information "Anti-GSDMD, clone 6D11"

Protein function: [Gasdermin-D]: Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed:26375003, PubMed:26375259, PubMed:27281216). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:26375003, PubMed:26375259, PubMed:27281216). {ECO:0000269, PubMed:26375003, ECO:0000269, PubMed:26375259, ECO:0000269, PubMed:27281216}. [The UniProt Consortium]

Keywords:	Anti-Gasdermin-D, N-terminal {ECO:0000305}, Anti-Gasdermin-D, C-terminal {ECO:0000305}, Anti-GSDMD-NT {ECO:0000250\|UniProtKB:Q9D8T2}, Anti-GSDMD-CT {ECO:0000250\|UniProtKB:Q9D8T2}, Anti-hGSDMD-NTD {ECO:0000303\|PubMed:31097341}, Anti-hGSDMD-CTD {ECO:0000303
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG43428

Properties

Application:	FC, ICC, IF, IHC (paraffin), WB
Antibody Type:	Monoclonal
Clone:	6D11
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant protein corresponding to M1-H484 of Human GSDMD
MW:	53 kD
Format:	Antigen Affinity Purified