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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-PACO49258.50 | 50 µg | - |
9 - 20 business days* |
363.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
GRHL3 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and... more
Product information "Anti-GRHL3"
GRHL3 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IF applications. GRHL3 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Transcription factor playing important roles in primary neurulation and in the differentiation of stratified epithelia of both ectodermal and endodermal origin. Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' acting as an activator and repressor on distinct target genes (PubMed:21081122, PubMed:25347468). xhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair. Exhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair but is essential to form the epidermal barrier with TGM3 as critical direct target gene among others. Despite being dispensable during normal epidermal homeostasis in the adulthood, is again required for barrier repair after immune-mediated epidermal damage, regulates distinct gene batteries in embryonic epidermal differentiation and adult epidermal barrier reformation after injury. Plays unique and cooperative roles with GRHL2 in establishing distinct zones of primary neurulation. Essential for spinal closure, functions cooperatively with GRHL2 in closure 2 (forebrain/midbrain boundary) and posterior neuropore closure. Also required for proper development of the oral periderm (PubMed:24360809). No genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity (PubMed:21081122). [The UniProt Consortium]
Keywords: | Anti-SOM, Anti-Sister of mammalian grainyhead, Anti-Transcription factor CP2-like 4, Anti-Grainyhead-like protein 3 homolog |
Supplier: | Assay Genie |
Supplier-Nr: | PACO49258 |
Properties
Application: | ELISA, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Human Grainyhead-like protein 3 homolog protein (31-182AA) |
Database Information
KEGG ID : | K09275 | Matching products |
UniProt ID : | Q8TE85 | Matching products |
Gene ID : | GeneID 57822 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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