Anti-GPR1

Anti-GPR1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES5574.50 50 µl - -

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169.00€
ELK-ES5574.100 100 µl - -

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283.00€
 
function:Orphan receptor. Probable opioid receptor. Can act as a co-receptor for... more
Product information "Anti-GPR1"
function:Orphan receptor. Probable opioid receptor. Can act as a co-receptor for HIV-1.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in hippocampus., Protein function: Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis (PubMed:18165312, PubMed:27716822). Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too (PubMed:27716822). Acts also as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway. [The UniProt Consortium] Recommended dilutions: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.. Cellular localization: Cell membrane , Multi-pass membrane protein . Internalizes in presence of its ligand, TAFA1 (By similarity). Internalizes efficiently in response to RARRES2 (PubMed:27716822). .
Keywords: Anti-Chemerin-like receptor 2, Anti-Chemokine-like receptor 2, Anti-G-protein coupled receptor 1, Anti-Chemerin chemokine-like receptor 2, GPR1 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES5574

Properties

Application: IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: The antiserum was produced against synthesized peptide derived from human GPR1. AA range:121-170
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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