Anti-GPBAR1 / TGR5

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ6993 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The G protein-coupled bile acid receptor 1... more
Product information "Anti-GPBAR1 / TGR5"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor for bile acids (M-BAR) and TGR5 as is a protein that in humans is encoded by the GPBAR1 gene. This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. Protein function: Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. [The UniProt Consortium]
Keywords: Anti-TGR5, Anti-BG37, Anti-M-BAR, Anti-hBG37, Anti-GPBAR1, Anti-hGPCR19, Anti-G-protein coupled receptor GPCR19, Anti-Membrane-type receptor for bile acids, Anti-G-protein coupled bile acid receptor 1, GPBAR1 Antibody / TGR5
Supplier: NSJ Bioreagents
Supplier-Nr: RQ6993

Properties

Application: WB, FC, Direct ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant human protein (amino acids N76-S310)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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