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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V9078-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V9078-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. By immunohistochemistry, it... more
Product information "Anti-gp100, clone SPM142"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This mAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. It stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. Protein function: Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. [The UniProt Consortium]
Keywords: | Anti-PMEL, Anti-D12S53E, gp100 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V9078 |
Properties
Application: | FC, IF, IHC |
Antibody Type: | Monoclonal |
Clone: | SPM142 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Extract of pigmented melanoma metastases from lymph nodes was used as the immunogen for this gp100 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K17304 | Matching products |
UniProt ID : | P40967 | Matching products |
Gene ID | GeneID 6490 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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