Anti-GMNN

Anti-GMNN
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA054597.25 25 µl -

7 - 10 business days*

320.00€
ATA-HPA054597.100 100 µl -

7 - 10 business days*

450.00€
 
Protein function: Inhibits DNA replication by preventing the incorporation of MCM complex into... more
Product information "Anti-GMNN"
Protein function: Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC) (PubMed:9635433, PubMed:14993212, PubMed:20129055, PubMed:24064211). It is degraded during the mitotic phase of the cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Its destruction at the metaphase- anaphase transition permits replication in the succeeding cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing (PubMed:20129055). Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control (PubMed:22615398). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 65% and to rat: 65%
Keywords: Anti-GMNN, Anti-Geminin
Supplier: Atlas Antibodies
Supplier-Nr: HPA054597

Properties

Application: ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GRENELSAGL SKRKHRNDHL TSTTSSPGVI VPESSENKNL GGVTQESFDL MIKENPSSQY WK (ATA-APrEST91555)

Database Information

KEGG ID : K10749 | Matching products
UniProt ID : O75496 | Matching products
Gene ID : GeneID 51053 | Matching products
Protein Atlas Nr. : ENSG00000112312

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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