Anti-Glucagon [Guinea Pig]

Glucagon is a common constituent of endocrine pancreatic tumors and of rectal carcinoids. The antibody is specific to pancreatic glucagon. Absorption with 10-100 µg glucagon per ml diluted antiserum abolishes the staining. Tested on human and cat tissues Protein function: [Glucagon]: Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. [The UniProt Consortium]