Anti-Glicentin [Rabbit]

Glicentin contains the glucagon sequence and is produced in endocrine cells of the distal intestine, in pancreatic glucagon cells and in the nerves in the brain.
This glicentin antibody is reactive with glycentin as well as glucagon. The antibody can be used for the diagnosis of tumors from the distal intestine (rectal carcinoids) as well as pancreatic islet cell tumors.
Positive control: Pancreas, small intestine. Protein function: [Glucagon]: Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. [The UniProt Consortium]