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![Anti-GITR / TNFRSF18](https://www.biomol.com/media/image/af/12/3e/NSJ-R32938_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R32938 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tumor necrosis factor receptor superfamily... more
Product information "Anti-GITR / TNFRSF18"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. [The UniProt Consortium]
Keywords: | Anti-AITR, Anti-CD357, Anti-TNFRSF18, Anti-Activation-inducible TNFR family receptor, Anti-Glucocorticoid-induced TNFR-related protein, Anti-Tumor necrosis factor receptor superfamily member 18, GITR Antibody / TNFRSF18 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R32938 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | mouse, rat |
Immunogen: | A recombinant human protein corresponding to amino acids L178-V241 was used as the immunogen for the GITR antibody. |
Format: | Purified |
Database Information
KEGG ID : | K05154 | Matching products |
UniProt ID : | Q9Y5U5 | Matching products |
Gene ID | GeneID 8784 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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