Anti-GFRA1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R31615 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. GDNF family receptor alpha-1, also known... more
Product information "Anti-GFRA1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. GDNF family receptor alpha-1, also known as the GDNF receptor, is a protein that in humans is encoded by the GFRA1 gene. It is mapped to chromosome 10q25.3. The protein encoded by this gene is a member of the GDNF receptor family. GFRA1 is released by neuronal cells, Schwann cells, and injured sciatic nerve. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is also a candidate gene for Hirschsprung disease. Soluble GFRA1 mediates robust recruitment of RET to lipid rafts via a mechanism requiring the RET tyrosine kinase. Protein function: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. [The UniProt Consortium]
Keywords: Anti-Gfra1, Anti-Gdnfra, Anti-GFR-alpha-1, Anti-GDNFR-alpha-1, Anti-GDNF receptor alpha-1, Anti-GDNF family receptor alpha-1, Anti-TGF-beta-related neurotrophic factor receptor 1, GFRA1 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R31615

Properties

Application: WB, IHC (paraffin)
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Human partial recombinant protein (AA 25-227)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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