Anti-GC, ID (GBA, GC, GLUC, Glucosylceramidase, Acid beta-glucosidase, Alglucerase, Beta-glucocerebr

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100~1600, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.