Anti-GAPDH, clone GA1R

Anti-GAPDH, clone GA1R
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Save 30% on all primary antibodies by Arigo Biolaboratories!

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*1 Offer expires 16/12/2024
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
ARG62345.50 50 µg - -

6 - 14 business days*

30 %
276.00€
193.20€
 
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities,... more
Product information "Anti-GAPDH, clone GA1R"
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. [The UniProt Consortium]
Keywords: Anti-Gapd, Anti-GAPDH, Anti-Gapdh, EC=2.6.99.-, EC=1.2.1.12, Anti-Peptidyl-cysteine S-nitrosylase GAPDH, Anti-Glyceraldehyde-3-phosphate dehydrogenase
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG62345

Properties

Application: DB, ELISA, ICC, IF, WB
Antibody Type: Monoclonal
Clone: GA1R
Conjugate: No
Host: Mouse
Species reactivity: human, mouse, rat, chicken, e. coli, hamster, insect, swine, rabbit, s. cerevisiae
Immunogen: Recombinant GAPDH
MW: 37 kD

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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