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![Anti-Galectin-9 (human), Azide Free Clone B-T33 [Mouse]](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
DC-857.940.000 | 200 µg (200 µl) | - |
3 - 8 business days* |
204.00€
|
|||
DC-857.940.005 | 500 µg (500µl) | - |
3 - 8 business days* |
432.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Specificity: Recognises both natural and recombinant human Galectin-9 protein, Format:... more
Product information "Anti-Galectin-9 (human), Azide Free Clone B-T33 [Mouse]"
Specificity: Recognises both natural and recombinant human Galectin-9 protein, Format: Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free, Storage: Stable at +2-8°C for 12 months. For longer storage, freeze aliquots, Application Notes: Suitable for ELISA, Suitable for Flow Cytometry Protein function: Binds galactosides (PubMed:18005988). Has high affinity for the Forssman pentasaccharide (PubMed:18005988). Ligand for HAVCR2/TIM3 (PubMed:16286920). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (PubMed:16286920). Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth. Ligand for P4HB, the interaction retains P4HB at the cell surface of Th2 T-helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307). Ligand for CD44, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function. Promotes ability of mesenchymal stromal cells to suppress T-cell proliferation (PubMed:23817958). Expands regulatory T-cells and induces cytotoxic T-cell apoptosis following virus infection (PubMed:20209097). Activates ERK1/2 phosphorylation inducing cytokine (IL-6, IL-8, IL-12) and chemokine (CCL2) production in mast and dendritic cells (PubMed:24465902, PubMed:16116184). Inhibits degranulation and induces apoptosis of mast cells (PubMed:24465902). Induces maturation and migration of dendritic cells (PubMed:25754930, PubMed:16116184). Inhibits natural killer (NK) cell function (PubMed:23408620). Can transform NK cell phenotype from peripheral to decidual during pregnancy (PubMed:25578313). Astrocyte derived galectin-9 enhances microglial TNF production. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. May provide the molecular basis for urate flux across cell membranes, allowing urate that is formed during purine metabolism to efflux from cells and serving as an electrogenic transporter that plays an important role in renal and gastrointestinal urate excretion. Highly selective to the anion urate. [The UniProt Consortium]
Keywords: | Mouse Anti-Human Galectin-9 Monoclonal Antibody, Azide Free Clone B-T33, Anti-Gal-9, Anti-LGALS9, Anti-Ecalectin, Anti-Galectin-9, Anti-Tumor antigen HOM-HD-21 |
Supplier: | Diaclone |
Supplier-Nr: | 857.940 |
Properties
Application: | ELISA, FC |
Antibody Type: | Monoclonal |
Clone: | B-T33 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant human Galectin-9 |
Database Information
KEGG ID : | K10093 | Matching products |
UniProt ID : | O00182 | Matching products |
Gene ID | GeneID 3965 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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