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![Anti-GABRA1](https://www.biomol.com/media/image/9a/a2/f0/ATA-HPA055746-100_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA055746.100 | 100 µl | - |
7 - 10 business days* |
421.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Ligand-gated chloride channel which is a component of the heteropentameric... more
Product information "Anti-GABRA1"
Protein function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:23909897, PubMed:25489750, PubMed:29950725). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:23909897, PubMed:25489750). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity (PubMed:23909897, PubMed:25489750). GABRA1-mediated plasticity in the orbitofrontal cortex regulates context-dependent action selection. Functions also as histamine receptor and mediates cellular responses to histamine. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: | Anti-GABRA1, Anti-GABA(A) receptor subunit alpha-1, Anti-Gamma-aminobutyric acid receptor subunit alpha-1 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA055746 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KPKKVKDPLI KKNNTYAPTA TSYTPNLARG DPGLATIAKS ATIEPKEVKP E (ATA-APrEST86092) |
Database Information
KEGG ID : | K05175 | Matching products |
UniProt ID : | P14867 | Matching products |
Gene ID | GeneID 2554 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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