Anti-GABRA1

Anti-GABRA1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA055746.100 100 µl -

7 - 10 business days*

421.00€
 
Protein function: Ligand-gated chloride channel which is a component of the heteropentameric... more
Product information "Anti-GABRA1"
Protein function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:23909897, PubMed:25489750, PubMed:29950725). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:23909897, PubMed:25489750). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity (PubMed:23909897, PubMed:25489750). GABRA1-mediated plasticity in the orbitofrontal cortex regulates context-dependent action selection. Functions also as histamine receptor and mediates cellular responses to histamine. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: Anti-GABRA1, Anti-GABA(A) receptor subunit alpha-1, Anti-Gamma-aminobutyric acid receptor subunit alpha-1
Supplier: Atlas Antibodies
Supplier-Nr: HPA055746

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KPKKVKDPLI KKNNTYAPTA TSYTPNLARG DPGLATIAKS ATIEPKEVKP E (ATA-APrEST86092)

Database Information

KEGG ID : K05175 | Matching products
UniProt ID : P14867 | Matching products
Gene ID : GeneID 2554 | Matching products
Protein Atlas Nr. : ENSG00000022355

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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