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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A302-282A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A302-282A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Splicing factor that in its dephosphorylated form acts as a general repressor... more
Product information "Anti-FUSIP1"
Protein function: Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing (PubMed:11684676, PubMed:12419250, PubMed:14765198). Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70 (PubMed:14765198). Required for splicing repression in M-phase cells and after heat shock (PubMed:14765198). Also acts as a splicing factor that specifically promotes exon skipping during alternative splicing (PubMed:26876937). Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing (PubMed:26876937). May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator (PubMed:12419250). [The UniProt Consortium]
Keywords: | Anti-TASR, Anti-SRrp40, Anti-FUSIP1, Anti-SRSF10, Anti-Splicing factor SRp38, Anti-TLS-associated SR protein, Anti-40 kDa SR-repressor protein, Anti-TLS-associated serine-arginine protein, Anti-TLS-associated protein with SR repeats |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A302-282A |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: mouse, rat, bovine, pig, orangutan, white-tufted-ear marmoset) |
Immunogen: | synthetic peptide. The epitope recognized by A302-282A-T maps to a region between residue 133 and 183 of human FUS interacting protein (serine/arginine-rich) 1 using the numbering given in entry NP_006616.1 (GeneID 10772). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K12900 | Matching products |
UniProt ID : | O75494 | Matching products |
Gene ID : | GeneID 10772 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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