Anti-FOLR1

Anti-FOLR1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-19878.20 20 µl -

7 - 16 business days*

71.00€
E-AB-19878.60 60 µl -

7 - 16 business days*

143.00€
E-AB-19878.120 120 µl -

7 - 16 business days*

238.00€
E-AB-19878.200 200 µl -

7 - 16 business days*

396.00€
 
Folate receptor 1 (FOLR1),also known as folate receptor alpha or adult folate-binding protein... more
Product information "Anti-FOLR1"
Folate receptor 1 (FOLR1),also known as folate receptor alpha or adult folate-binding protein (FBP),is a 38-kDa glycoprotein belonging to the folate receptor family . The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung,kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer,non-small cell lung cancer,breast cancer,kidney cancer and high-grade osteosarcoma . Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. [The UniProt Consortium]
Keywords: Anti-FBP, Anti-FOLR, Anti-FOLR1, Anti-FR-alpha, Anti-KB cells FBP, Anti-Folate receptor 1, Anti-Folate receptor alpha, Anti-Folate receptor, adult, Anti-Adult folate-binding protein, Anti-Ovarian tumor-associated antigen MOv18, FOLR1 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-19878

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthetic peptide of human FOLR1

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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